oncologists and radiation therapists met in June in Prague at the annual conference of the European Society for Hyperthermic Oncology (ESHO), and discussed the latest studies and experiences of hyperthermia. Hyperthermia is a supportive treatment in cancer therapy to improve the treatment success of classical therapies. As reported on the current conference, U.S. researchers were able to show that it was possible through the use of hyperthermia in addition to radiotherapy treated patients with recurrent breast cancer successfully. In addition, the results of a new international study of Unversitätsklinikums Munich presents for hyperthermia for soft tissue sarcoma. In the world's first randomized controlled phase III study, the researchers demonstrated the effectiveness of regional hyperthermia in combination with chemotherapy in sarcomas. The fact that different types of tumors, hyperthermia in combination with standard therapy in certain cases may be appropriate, is already known for some time. This is the case for certain types of prostate and colon cancer. Also for lung cancer, there is a positive combination therapy study results.
working principle and applications
The principle of hyperthermia, a warming of the body or the tumor to about 40 ° C by the action of the conventional Therapy should be strengthened. A possible application of hyperthermia is dependent on the type, location and spread of the tumor.
In Germany, the combination treatment with standard therapy and hyperthermia is not yet used in routine, as there are too few scientific investigations. In malignant diseases, can be addressed by means of a standard treatment (surgery, radiotherapy, chemotherapy) with good to very good results, therefore, hyperthermia is not used. In general, typical areas of difficult cases of disease, such as recurrent
tumors that occur after conventional treatment again or bad or unresectable locally advanced tumors.
use forms of hyperthermia
Local H. In limited, superficial tumors are
applicators (antennas) mounted on the tumor, emit electromagnetic waves and thus heat up the tissue.
Regional H.: In low-lying tumors, the patient is surrounded by a ring-shaped applicator, the coupling of energy occurs in the water bolus (water irrigation).
partial body-H. A larger region in the abdomen or lower abdomen is heated with magnetic resonance monitoring.
Full-H. Heating of the entire body to 41-42 ° C is, for example in a steam-saturated chamber with water flowing through tubes, the energy can also be generated by infrared lamps.
thermal ablation: applicators are placed in small tumors and destroy by achievement of Tmperaturniveaus of 80 ° C or more cancer cells.
Interstitial H. antennas are placed in the tumor or introduced via hollow organs to him, usually combined with interstitial radiotherapy.
limb: On the feeding artery and the efferent vein of a limb is heated the blood through an external heat exchanger.
Further information on hyperthermia visit the website of www.hyperthermie.org Interdispziplinären hyperthermia group of the German Cancer Society eV
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