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consequences of tumor growth

malignant tumor growth, the consequences for the organism are very diverse and very different in each patient individually pronounced. Tumor growth can lead to a directly to local effects in the neighboring tissue. On the other tumors can also cause systemic (whole organism-related) effects. Key to the disease process often is the formation of secondary tumors, which may in turn lead to the institutions concerned on a number of disorders [9].

Local effects

If growing tumors, they may crowd out the healthy neighboring tissue without destroying it or destructive grow into the surrounding tissues (invasive-destructive growth). Both forms of growth can lead to local complications. For example, by expansive growth of a blood vessel leading compressed. Which occurs as a result of circulatory disturbance-dependent tissue can cause this tissue dies (necrosis). Infiltrative, destructive growth, for example, in hollow organs like the intestine through the destruction of the tissue to openings (perforations) and fistulae lead. Tumorfisteln often lead to further complications due to infections [9].

Systemic effects

tumors can affect in different ways the whole organism. From the primary tumor outgoing secondary tumors in other organs can settle here and destroy tissue by local growth and cause malfunctions. For many patients experience during their cancer to a general loss of strength and weight loss (cachexia, wasting). The systemic effects of tumors, so-called paraneoplastic syndromes are calculated. This results in characteristic symptoms in various organ systems that are ultimately caused by the tumor. For example, a lung cancer lead to a disruption of the hormonal regulation of water balance (Schwartz-Bartter syndrome) [9].

Most patients do not die on the primary tumor but from its metastases. The uncontrolled proliferation steals most of the metastases vital organs until they its function can not comply. Frequent direct causes of death are occlusions (thromboembolism), or no longer controllable by the organism infections (septicemia, blood poisoning).